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{"filename":"bsc-2-year-bt-immunology-and-immunotechnology-ns-3468-jun-2022.pdf","subject":"Immunology and Immunotechnology (B-205)","exam":"B.Sc. (Biotechnology) Second Year Examination, June 2022","sections":["Descriptive Answer Questions"]}

Questions:

  1. Define and classify antigen, antibody reaction. Discuss agglutination test with examples.
  2. What is humoral immunity? How does it differ from cell-mediated immunity? Explain.
  3. Write short notes on: (a) Pernicious anaemia (b) Rheumatoid Arthritis (c) Hashimoto's thyroiditis.
  4. Define hybridoma technology. Discuss its utility for the production of monoclonal antibodies and write its applications.
  5. Write short notes on: (a) MHC complex (b) Abnormal Immunoglobulin (c) Type IV Hypersensitivity Reaction (d) Acquired immunity.
  6. What is immunoelectrophoresis? What is the meaning of the terms RIA and IRMA?
  7. What are antigenic determinants on immunoglobulin? Provide an account of each type: isotype, idiotype, and allotype.
  8. Give a concise account of the nature of vaccines. Discuss the role of biotechnology in the development of new methods for vaccine production.
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