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Semester 5: Animal Physiology

  • Digestion - Overview of vertebrate digestive system

    Digestion - Overview of Vertebrate Digestive System
    • Introduction to Digestion

      Digestion is the biochemical process where food is broken down into smaller components, allowing for nutrient absorption. Vertebrate digestive systems have evolved to efficiently process diverse diets.

    • Structural Components of the Digestive System

      The vertebrate digestive system consists of a series of organs including the mouth, esophagus, stomach, intestines, liver, and pancreas. Each organ plays a specific role in the digestion and absorption of nutrients.

    • Function of the Mouth and Esophagus

      The mouth is where digestion begins through mechanical breakdown and enzymatic action (saliva). The esophagus is a muscular tube that transports food from the mouth to the stomach.

    • The Stomach and Its Role

      The stomach is a key organ where food is mixed with gastric juices. It helps in the chemical breakdown of food, particularly proteins, through the action of enzymes and acid.

    • Small Intestine Functionality

      The small intestine is where most nutrient absorption occurs. It consists of three parts: duodenum, jejunum, and ileum, each playing a role in further digestion and absorption.

    • The Large Intestine

      The large intestine absorbs water and salts from indigestible food matter, and compacts waste into feces. It also houses beneficial bacteria that assist in digestion.

    • Accessory Organs of Digestion

      Accessory organs, such as the liver and pancreas, produce enzymes and bile that are essential for digestion. The liver processes nutrients and detoxifies harmful substances, while the pancreas secretes digestive enzymes.

    • Digestive Processes in Different Vertebrates

      Digestive systems vary among vertebrates based on diet and habitat. Herbivores often have complex stomachs for breaking down plant material, while carnivores have simpler systems for digesting protein.

    • Conclusion

      The vertebrate digestive system is a complex and efficient mechanism that adapts to various dietary needs. Understanding its structure and function is essential for studying animal physiology.

  • Salivary glands - Pancreas - Liver

    Salivary glands, Pancreas, Liver
    Salivary glands are exocrine glands located in the oral cavity that produce saliva.
    • Moistening food for easier swallowing

    • Initiating the digestion of carbohydrates through enzymes like amylase

    • Providing antimicrobial action to protect the mouth

    Near the ear
    Serous fluid rich in amylase
    Under the jaw
    Mixed serous and mucous fluid
    Under the tongue
    Predominantly mucous fluid
    The pancreas is a glandular organ that has both exocrine and endocrine functions.
    • Producing digestive enzymes such as lipase, proteases, and amylase

    • Regulating blood sugar levels through insulin and glucagon secretion

    Secretes digestive juices into the small intestine.
    • Amylase

    • Lipase

    • Proteases

    Regulates metabolism and blood sugar.
    • Insulin

    • Glucagon

    The liver is the largest internal organ and a key player in metabolism, detoxification, and digestion.
    • Synthesis of biochemicals necessary for digestion

    • Detoxification of harmful substances

    • Storage of glycogen, vitamins, and minerals

    • Production of blood-clotting factors

    The liver produces bile, which is stored in the gallbladder and aids in fat emulsification.
    Essential for the digestion and absorption of dietary fats
  • Enzymes involved, digestive process in vertebrates

    Enzymes involved in digestive process in vertebrates
    • Introduction to Digestive Enzymes

      Digestive enzymes are biological catalysts that facilitate the breakdown of food into smaller, absorbable molecules. They are crucial for the digestive process in vertebrates, allowing for the efficient extraction of nutrients.

    • Types of Digestive Enzymes

      1. Amylases: Break down carbohydrates into simple sugars. Found in saliva and pancreatic juice. 2. Proteases: Degrade proteins into peptides and amino acids. Secreted by the stomach and pancreas. 3. Lipases: Digest fats into fatty acids and glycerol. Produced by the pancreas and released into the small intestine.

    • Enzyme Activity in Different Digestive Organs

      1. Mouth: Salivary amylase initiates carbohydrate digestion. 2. Stomach: Gastric juice contains pepsin (protease) and gastric lipase (lipid digestion). 3. Small Intestine: Pancreatic enzymes and brush border enzymes continue the digestion of carbohydrates, proteins, and fats.

    • Regulation of Enzyme Secretion

      Hormonal and neural signals regulate the secretion of digestive enzymes. The presence of food in the stomach and small intestine triggers the release of hormones like gastrin, secretin, and cholecystokinin, which then stimulate enzymatic activity.

    • Factors Affecting Enzyme Activity

      1. pH: Each enzyme has an optimal pH range (e.g., pepsin works best in acidic conditions). 2. Temperature: Enzymes operate within a specific temperature range; high temperatures can denature enzymes. 3. Substrate Concentration: Increased substrate concentration can enhance enzyme activity up to a saturation point.

  • Respiratory system - Structure and function in fish and mammals

    Respiratory system - Structure and function in fish and mammals
    • Overview of Respiratory Systems

      Respiratory systems facilitate gas exchange in organisms. Different classes of animals have adapted various structures to meet their oxygen demands. Fish use gills, while mammals utilize lungs.

    • Respiratory System in Fish

      Fish possess gills, which are specialized organs for extracting oxygen from water. Gills are composed of filaments containing capillaries for blood exchange. Water enters through the mouth, flows over the gills, and exits through the gill slits, enabling efficient oxygen uptake and carbon dioxide expulsion.

    • Respiratory System in Mammals

      Mammals possess lungs, which are internal structures allowing for gas exchange within a moist environment. Air enters through the nose or mouth, travels down the trachea, and into the bronchi leading to the lungs. Alveoli, tiny air sacs in the lungs, facilitate the exchange of oxygen and carbon dioxide with the bloodstream.

    • Comparative Anatomy of Respiratory Structures

      Gills in fish are efficient for extracting oxygen from water due to the high surface area provided by gill filaments and lamellae. In contrast, mammalian lungs have large surface areas due to alveoli, optimizing gas exchange efficiency in air.

    • Mechanism of Breathing

      Fish utilize a form of buccal pumping to draw water over their gills. Mammals use negative pressure breathing, where the diaphragm and intercostal muscles expand the thoracic cavity, drawing air into the lungs.

    • Adaptations for Respiratory Efficiency

      Fish adaptations include countercurrent exchange in gills to maximize oxygen absorption. Mammals have adaptations such as increased lung surface area and a highly vascularized alveolar structure to enhance oxygen uptake.

    • Respiratory Control Mechanisms

      Both fish and mammals regulate their respiratory processes via nervous and chemical signals. In mammals, the medulla oblongata plays a crucial role in controlling the rate and depth of breathing based on carbon dioxide levels in the blood.

  • Transport of oxygen and carbon dioxide

    • Introduction to Gas Transport

      In animals, oxygen and carbon dioxide are transported primarily through the circulatory system. Oxygen is essential for cellular respiration, whereas carbon dioxide is a byproduct of this process.

    • Oxygen Transport in the Blood

      Oxygen is carried in the blood mainly by hemoglobin in red blood cells. Each hemoglobin molecule can bind to four oxygen molecules, facilitating efficient oxygen delivery to tissues.

    • Mechanisms of Oxygen Uptake

      Oxygen is taken up by the lungs during inhalation. It then diffuses across the alveolar membrane into the blood, driven by a concentration gradient.

    • Transport of Carbon Dioxide

      Carbon dioxide is transported in the blood in three forms: dissolved in plasma, as bicarbonate ions, and bound to hemoglobin. The majority is converted to bicarbonate in red blood cells.

    • Mechanisms of Carbon Dioxide Release

      Carbon dioxide is released from tissues into the blood and primarily expelled from the body through the lungs during exhalation.

    • Role of the Respiratory System

      The respiratory system facilitates the exchange of gases between the atmosphere and the blood, crucial for maintaining oxygen and carbon dioxide homeostasis.

    • Adaptations in Gas Transport

      Various adaptations exist in different animal species for efficient gas transport, including changes in hemoglobin affinity for oxygen in response to environmental conditions.

    • Conclusion

      The efficient transport of oxygen and carbon dioxide is vital for cellular functions in animals. Understanding these processes is key to the study of animal physiology.

  • Circulatory system - Heart - Blood vessels - Blood pressure

    Circulatory system - Heart - Blood vessels - Blood pressure
    • Overview of the Circulatory System

      The circulatory system is a complex network that includes the heart, blood vessels, and blood. It is responsible for the transportation of nutrients, gases, hormones, and waste products throughout the body, ensuring that tissues receive the necessary substances for proper function.

    • The Heart

      The heart is a muscular organ that pumps blood throughout the body. It consists of four chambers: the left atrium, right atrium, left ventricle, and right ventricle. Each chamber has a specific function in the circulation process, with the left side pumping oxygenated blood to the body and the right side pumping deoxygenated blood to the lungs for oxygenation.

    • Blood Vessels

      Blood vessels are the conduits through which blood flows. They include arteries, veins, and capillaries. Arteries carry oxygen-rich blood away from the heart, while veins return oxygen-poor blood back to the heart. Capillaries are small, thin-walled vessels where the exchange of gases, nutrients, and waste occurs at the tissue level.

    • Blood Pressure

      Blood pressure is the force exerted by circulating blood on the walls of blood vessels. It is essential for maintaining adequate blood flow to organs and tissues. Blood pressure is measured using two values: systolic pressure, which occurs during heartbeats, and diastolic pressure, which occurs between beats. Normal blood pressure is vital for overall health, and deviations can indicate various medical conditions.

  • Lymphatic system and its importance

    Lymphatic system and its importance
    • Introduction to the Lymphatic System

      The lymphatic system is a crucial part of the immune system and is responsible for maintaining fluid balance in the body. It consists of a network of lymphatic vessels, lymph nodes, and lymphatic organs.

    • Structure of the Lymphatic System

      The lymphatic system includes lymphatic vessels, which transport lymph; lymph nodes, which filter harmful substances; and organs such as the spleen and thymus that play roles in immune responses.

    • Functions of the Lymphatic System

      Key functions include transporting lymph, which contains white blood cells; draining excess interstitial fluid; distributing nutrients and waste products; and facilitating the absorption of fats from the digestive system.

    • Role in Immune Response

      The lymphatic system is vital for the body's defense against pathogens. Lymph nodes trap and destroy bacteria and viruses, while lymphatic vessels transport immune cells throughout the body.

    • Clinical Significance

      Disruptions in the lymphatic system can lead to medical conditions such as lymphedema, infections, and may contribute to the spread of cancer. Understanding its function is essential for diagnosing and treating these conditions.

    • Conclusion

      The lymphatic system plays an essential role in maintaining health, supporting immune function, and ensuring proper fluid balance. Its study is important in fields such as zoology, immunology, and medicine.

  • Excretory system - Structure and function in vertebrates

    Excretory system - Structure and function in vertebrates
    • Overview of the Excretory System

      The excretory system is responsible for the removal of waste products generated by metabolic processes, maintaining water and electrolyte balance in the body. It plays a crucial role in homeostasis.

    • Main Organs Involved

      The primary organs of the excretory system in vertebrates include the kidneys, ureters, bladder, and urethra. The kidneys filter blood to produce urine, which is transported by ureters to the bladder for storage before excretion.

    • Kidney Structure

      The kidney has an outer cortex and an inner medulla, containing nephrons which are the functional units. Each nephron consists of a renal corpuscle and renal tubules, facilitating filtration and absorption.

    • Kidney Function

      The kidneys perform ultrafiltration, reabsorption, and secretion to regulate blood composition. They filter waste products like urea and toxins from the blood while retaining necessary substances such as glucose and electrolytes.

    • Urine Formation

      Urine formation occurs in three stages: filtration at the glomerulus, reabsorption in the renal tubules, and secretion of additional wastes into the tubule. The final urine is collected in the renal pelvis.

    • Role of Hormones

      Hormones like aldosterone, antidiuretic hormone (ADH), and atrial natriuretic peptide (ANP) regulate kidney function by influencing water absorption and sodium balance, impacting blood pressure and volume.

    • Variations in Excretory Systems

      Different vertebrate classes exhibit variations in excretory systems. For example, amphibians may utilize both lungs and skin in addition to kidneys, while fish primarily excrete ammonia directly into water.

    • Clinical Relevance

      Understanding the excretory system is essential for diagnosing and treating kidney diseases, urinary tract infections, and electrolyte imbalances, which can have significant health implications.

  • Nervous system - Structure and functions

    Nervous system - Structure and functions
    • Overview of the Nervous System

      The nervous system is a complex network of neurons and supporting cells responsible for transmitting signals throughout the body. It is divided into the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS includes the brain and spinal cord, while the PNS consists of all other neural elements.

    • Structural Components of the Nervous System

      The primary structural components include neurons and glial cells. Neurons are the basic functional units that transmit information via electrical and chemical signals. Glial cells support and protect neurons, maintaining homeostasis and forming myelin.

    • Functions of the Nervous System

      The main functions include sensory input, information processing, and motor output. Sensory input involves receiving stimuli from the environment, processing involves interpreting this information, and motor output involves responding to stimuli through muscle contraction or gland secretion.

    • Types of Neurons

      Neurons can be classified into three main types: sensory neurons (afferent neurons), which transmit sensory information; motor neurons (efferent neurons), which send signals to muscles; and interneurons, which connect neurons within the CNS.

    • Neural Communication

      Neural communication occurs through action potentials and synaptic transmission. Action potentials are electrical impulses that travel along neurons, while synaptic transmission involves the release of neurotransmitters at synapses between neurons, facilitating signal transfer.

    • Nervous System Disorders

      Disorders of the nervous system can include neurodegenerative diseases, traumatic injuries, and infections. Common examples are Alzheimer's disease, Parkinson's disease, multiple sclerosis, and spinal cord injuries.

  • Endocrine glands and hormones

    Endocrine glands and hormones
    • Introduction to Endocrine System

      The endocrine system consists of glands that secrete hormones directly into the bloodstream. Hormones are chemical messengers that regulate various bodily functions, including metabolism, growth, and mood.

    • Major Endocrine Glands

      The major endocrine glands include the pituitary gland, thyroid gland, parathyroid glands, adrenal glands, pancreas, and gonads (ovaries and testes). Each gland has specific functions and hormone production.

    • Pituitary Gland

      Often referred to as the master gland, the pituitary gland controls other glands and produces hormones such as growth hormone, prolactin, and adrenocorticotropic hormone.

    • Thyroid Gland

      The thyroid gland produces thyroid hormones (T3 and T4) that regulate metabolism, energy generation, and overall growth. It plays a crucial role in the development of the nervous system.

    • Adrenal Glands

      Located on top of the kidneys, the adrenal glands produce hormones such as cortisol, which helps the body respond to stress, and adrenaline, which prepares the body for 'fight or flight' responses.

    • Pancreas and Hormonal Regulation of Blood Sugar

      The pancreas has both exocrine and endocrine functions. It produces insulin and glucagon, hormones that regulate blood sugar levels.

    • Hormonal Feedback Mechanisms

      The endocrine system operates on feedback mechanisms, primarily negative feedback, to maintain homeostasis. For example, high levels of thyroid hormones can inhibit the release of thyroid-stimulating hormone.

    • Effects of Hormones on Target Organs

      Hormones exert their effects on specific target organs by binding to receptors. This can trigger a cascade of cellular responses, influencing growth, metabolism, and various physiological processes.

    • Disorders of the Endocrine System

      Common endocrine disorders include diabetes, hyperthyroidism, and Addison's disease. These conditions often result from hormonal imbalances, affecting overall health and wellbeing.

  • Muscular system - Types of muscles, mechanism of contraction

    Muscular system
    • Types of Muscles

      There are three main types of muscles in the animal body: skeletal muscle, smooth muscle, and cardiac muscle. - Skeletal Muscle: Voluntary muscles that are attached to bones, enabling movement. They have a striated appearance and are under conscious control. - Smooth Muscle: Involuntary muscles found in the walls of internal organs, such as the intestines and blood vessels. They are non-striated and function automatically. - Cardiac Muscle: Involuntary striated muscle found only in the heart. It is responsible for the rhythmic contractions of the heart and operates autonomously.

    • Mechanism of Contraction

      Muscle contraction involves several cellular processes, primarily the sliding filament theory. This theory describes how muscle fibers contract and generate force: 1. **Neuromuscular Junction**: The contraction process begins when a motor neuron releases acetylcholine at the neuromuscular junction, stimulating the muscle fiber. 2. **Action Potential**: This stimulus generates an action potential that travels along the muscle fiber's membrane and down the T-tubules. 3. **Calcium Release**: The action potential triggers the release of calcium ions from the sarcoplasmic reticulum into the cytoplasm of the muscle fiber. 4. **Cross-Bridge Formation**: Calcium ions bind to troponin, causing a conformational change that allows myosin heads to attach to actin filaments, forming cross-bridges. 5. **Power Stroke**: The myosin heads pivot, pulling the actin filaments inward toward the center of the sarcomere, resulting in muscle shortening. 6. **Detachment and Resetting**: ATP binds to myosin, causing it to detach from actin. Hydrolysis of ATP resets the myosin head for another cycle of contraction.

    • Regulation of Muscle Contraction

      Muscle contraction is regulated primarily by the nervous system and endocrine factors: - **Nervous Control**: The frequency of nerve impulses influences contraction strength and duration. More frequent impulses lead to stronger contractions (summation). - **Hormonal Influence**: Hormones such as adrenaline can enhance muscle contraction during stress or excitement, affecting overall muscle performance.

  • Reproductive system - Male and female reproductive organs

    Reproductive system - Male and female reproductive organs
    • Overview of Reproductive System

      The reproductive system is responsible for producing offspring and ensuring the continuation of species. It includes specialized organs that facilitate the production of gametes and hormones.

    • Male Reproductive System

      The male reproductive system includes structures such as the testes, vas deferens, prostate gland, and penis. The testes produce sperm and testosterone, while the vas deferens transports sperm. The prostate gland contributes fluids to semen.

    • Female Reproductive System

      The female reproductive system consists of the ovaries, fallopian tubes, uterus, and vagina. Ovaries produce eggs and hormones like estrogen. The fallopian tubes transport the eggs, and the uterus is where embryo implantation occurs.

    • Comparative Anatomy of Reproductive Organs

      Male and female reproductive organs have distinct anatomical features suited for their specific functions. Males typically have external organs, while females have internal organs.

    • Hormonal Regulation

      The reproductive systems in both males and females are regulated by hormones. In males, testosterone is crucial for sperm production and secondary sexual characteristics. In females, estrogen and progesterone regulate the menstrual cycle and pregnancy.

    • Reproductive Health

      Reproductive health encompasses the physical, emotional, and social well-being related to the reproductive system. It includes education on sexual health, prevention of sexually transmitted infections, and access to reproductive healthcare.

  • Nervous control of reproduction

    Nervous control of reproduction
    • Introduction to Nervous Control

      The nervous system plays a crucial role in regulating reproductive processes in animals. It coordinates various physiological events necessary for reproduction, including hormonal release and reproductive behaviors.

    • Neuroendocrine Mechanisms

      Neuroendocrine mechanisms involve the interaction between the nervous system and the endocrine system. The hypothalamus releases gonadotropin-releasing hormone (GnRH), which stimulates the anterior pituitary gland to release luteinizing hormone (LH) and follicle-stimulating hormone (FSH), essential for gamete production.

    • Role of Autonomic Nervous System

      The autonomic nervous system, consisting of the sympathetic and parasympathetic divisions, regulates reproductive functions. The sympathetic division is involved in ejaculation and orgasm, while the parasympathetic division facilitates erection and arousal.

    • Influence of Environmental Factors

      External environmental factors, such as light and temperature, can influence the nervous control of reproduction. Light exposure affects the secretion of melatonin, which can impact reproductive cycles in seasonal breeders.

    • Behavioral Responses

      The nervous system governs reproductive behaviors, including courtship and mating rituals. These behaviors are influenced by sensory input and neural pathways that mediate attraction and pairing between mates.

    • Pathologies of Nervous Control

      Disorders affecting the nervous system can disrupt reproductive functions. Conditions such as spinal cord injuries or neurodegenerative diseases can lead to infertility or altered sexual behavior.

Animal Physiology

B.Sc Zoology

Zoology

5

Periyar University

23UZOCO08

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